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The Dangers of Combining Meth and Opioids

Written by Shannon Weir, RN | Updated on Sep 14, 2023

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Medically reviewed by Sara Kaylor, LCDC, LPC

Dangers of Combining Meth & Opioids

Risks of Mixing Methamphetamines and Hydrocodone (Vicodin®), Oxycodone (OxyContin®, Percocet®), Oxymorphone (Opana®), Morphine (Kadian®, Avinza®), Codeine, Fentanyl, Hydromorphone, Tapentadol, Methadone, and Heroin

The combined use of methamphetamine and opioids stands as a topic of critical concern. These two potent substances, when consumed in tandem, lead to a series of amplified and severe effects that warrant thorough investigation. The following discourse delves into the multifaceted dangers presented by this combination, providing a comprehensive understanding of the associated risks to individual and public health.

What is Meth?

Methamphetamine, commonly referred to as “meth,” is a powerful central nervous system stimulant that has captured headlines and the public’s attention due to its intense effects and the destruction it can cause in individuals and communities. Derived originally from its parent drug, amphetamine, meth was initially used in nasal decongestants and bronchial inhalers.

Chemical Composition and Forms of Meth

Meth looks like clear crystals, often referred to as “crystal,” “ice,” or “glass.” It can also be found in a white powder form, which can be ingested, snorted, smoked, or injected. Its chemical structure is similar to amphetamine but produces much stronger effects on the central nervous system.

Meth’s Effects on the User

When ingested, meth produces a rush of euphoria. This sensation is due to the massive release of dopamine in the brain. Dopamine plays a significant role in mood, motivation, pleasure, and reward systems of the brain. As a result, users often feel invincible, extremely alert, and energized. These effects make meth extremely addictive, as users chase that initial euphoria, often leading them to binge on the drug.

Meth Production:

Meth can be produced using over-the-counter drugs and chemicals, making it accessible for illicit home labs. The production process itself is dangerous and can result in explosions. Moreover, the chemicals used in meth production are toxic, polluting the areas where it’s made.

Methamphetamine’s Impact on Health

Prolonged meth use can lead to severe health consequences. Apart from the immediate side effects like increased heart rate and decreased appetite, meth can lead to severe dental problems, known colloquially as “meth mouth.” Regular users might experience extreme weight loss, skin sores, and even severe itching.

Addiction and Dependence:

The intense high of meth is followed by an intense crash, leading users to consume more to avoid the crash, making it a vicious cycle. Over time, users may require larger doses to achieve the same high, leading to increased dependence. This relentless cycle often results in a quick and severe addiction.

 

Understanding meth, its effects, and the potential risks associated with its use is crucial in battling its prevalence and supporting those looking to escape its grip.

What are Opioids?

Opioids are a broad group of pain-relieving drugs derived from opium or made synthetically. Historically, the opium poppy, used for thousands of years for both medicinal and recreational purposes, has been the source of these drugs. In modern times, opioids are used medically to treat moderate to severe pain, but they also have a high potential for misuse due to their euphoric effects and addictive properties.

Types of Opioids

There are several different types of opioids, including:

  • Natural Opiates: These are directly obtained from the opium poppy and include morphine and codeine.
  • Semi-synthetic Opioids: Created in labs from natural opiates. Examples include heroin (from morphine), hydrocodone, and oxycodone.
  • Synthetic Opioids: Fully man-made and include drugs like fentanyl, tramadol, and methadone.

How Opioids Work

Opioids bind to specific proteins called opioid receptors found in the brain, spinal cord, and gastrointestinal tract. When these drugs attach to these receptors, they block pain signals sent from the brain to the body and release large amounts of dopamine throughout the body, leading to intense feelings of relaxation and pleasure.

Medical Uses for Opioids

Opioids are potent painkillers. They’re often prescribed post-surgery, for cancer-related pain, or for severe chronic pain conditions. When used correctly and under the supervision of a medical professional, they can provide significant relief.

Risks and Side Effects

Regular opioid use, even as prescribed by a doctor, can lead to the development of tolerance, which means needing to take more of the drug to achieve the same effect. Over time, this can lead to physical dependence and then, potentially, to addiction. Side effects can include drowsiness, constipation, nausea, and, crucially, respiratory depression. Respiratory depression can be fatal if too much of the drug is taken.

Opioid Crisis

In recent years, the misuse of and addiction to opioids—including prescription pain relievers, heroin, and synthetic opioids such as fentanyl—has become a serious national crisis in various countries, notably the United States. This crisis has been marked by a staggering number of overdoses and deaths, putting pressure on communities and healthcare systems.

Treatment for Opioid Misuse and Addiction

Given the risks associated with opioids, various treatments are available for those struggling with addiction. Medications like methadone, buprenorphine, and naltrexone are used in combination with counseling and behavioral therapies to treat opioid addiction.

Understanding the nature, benefits, and dangers of opioids is vital, especially in today’s world, where opioid misuse has reached epidemic levels in certain regions. This knowledge can help individuals make informed decisions about their health and be more aware of the risks involved.

Dangers of Combining Meth and Opioids

The simultaneous consumption of methamphetamine and opioids represents a dangerous mixture of two potent substances. When integrated, these compounds can result in profound physiological and psychological ramifications. This section aims to explain the inherent dangers and complexities arising from this combination.

Pharmacological Conflict

  • Counteractive Effects: Meth acts as a stimulant, accelerating heart rate and increasing alertness, while opioids are depressants, slowing down bodily functions and inducing relaxation. When taken together, these substances send conflicting signals to the body. It’s akin to pressing the gas and brake pedals of a car simultaneously, leading to immense strain on the body’s systems.
  • Masking Overdose Symptoms: The stimulating effects of meth can sometimes mask the signs of an opioid overdose. A user might not recognize slowed or irregular breathing caused by opioids due to the alertness and energy from meth. This can delay crucial medical interventions.

Enhanced Harms

  • Cardiovascular Strain: Both meth and opioids, individually, exert significant stress on the cardiovascular system. When combined, the risk of heart attacks, strokes, and other cardiovascular issues amplifies.
  • Neurological Impacts: Meth affects dopamine release, while opioids primarily influence the body’s endorphin levels. Their simultaneous consumption can throw the brain’s chemistry off-balance, leading to unpredictable mood swings, increased paranoia, and cognitive impairments.

Mental Health Deterioration

  • Heightened Psychosis: Meth use alone can induce psychosis characterized by hallucinations and delusional thoughts. When opioids, which can cause confusion and depression, are added to the mix, the potential for severe psychological disturbances grows exponentially.
  • Deepening Dependence: The euphoria from the combination can be so intense that users might find it harder to resist the urge to use again, driving a deeper dependence on both substances.

Overdose Potential

  • Synergistic Toxicity: Each of these drugs has its toxic levels. When used together, they can achieve toxic effects at lower levels than when used individually due to synergistic toxicity.
  • Complex Treatment: In the event of an overdose, medical professionals are faced with the challenge of treating complications from two powerful drugs, which complicates and delays the treatment process.

In essence, the dangers of combining meth and opioids are profound and multi-faceted. The repercussions span across the physical, psychological, and societal realms, making it a pressing concern for both the individual user and the broader community. Awareness and education about these dangers are pivotal in curbing this risky behavior.

Methamphetamine Interactions With Specific Opioids

The co-ingestion of methamphetamine and opioids can introduce a myriad of risks. When combined with specific opioids, methamphetamine can have unique interactions that amplify the dangers of each substance. Below is an examination of the potential risks associated with the combination of methamphetamine and several commonly used opioids:

The Risks of Mixing Meth and Hydrocodone (Vicodin®)

Hydrocodone, a semi-synthetic opioid, is commonly prescribed for moderate pain. When taken alongside methamphetamine, users may not only experience enhanced euphoria but also face heightened risks. Meth’s stimulating properties can overshadow hydrocodone’s sedative effects, potentially leading users to consume higher doses in search of the opioid’s calming effect, unknowingly bringing them closer to respiratory failure or overdose.

The Risks of Mixing Meth and Oxycodone (OxyContin®, Percocet®)

Oxycodone is widely recognized for its potent analgesic properties. The interaction with meth elevates cardiovascular risks. Simultaneous consumption can create a false sense of alertness, prompting users to take excessive amounts of oxycodone, increasing the chances of cardiac arrest or stroke.

The Risks of Mixing Meth and Oxymorphone (Opana®)

Oxymorphone, another potent opioid analgesic, has strong sedative properties. Its combination with meth can lead to suppressed respiratory function due to the opioid’s effects, which may not be immediately noticeable because of meth’s stimulatory properties. The combination may result in unexpected and sudden respiratory failure.

The Risks of Mixing Meth and Morphine (Kadian®, Avinza®)

Morphine has been the cornerstone of pain management for decades. The combination of this classic opioid with meth poses a dual threat to the cardiovascular system. The duality of stimulation and depression in the heart and circulatory system increases the likelihood of cardiac irregularities and failure.

The Risks of Mixing Meth and Codeine

Codeine, often used for milder pain or as a cough suppressant, might seem less dangerous due to its lower potency relative to other opioids. However, when paired with meth, neurological and respiratory risks surge. The central nervous system can become erratic, leading to potential seizures and breathing difficulties.

The Risks of Mixing Meth and Fentanyl

Fentanyl’s potency is well-documented, being 50 to 100 times more potent than morphine. Even trace amounts, when combined with meth, can lead to catastrophic results. The combined respiratory depression from fentanyl and cardiovascular stimulation from meth can quickly lead to organ failure or death.

The Risks of Mixing Meth and Hydromorphone

Known for its rapid onset and potent analgesic effects, hydromorphone poses significant risks when combined with meth. The body may experience dehydration at accelerated rates, increasing the strain on the kidneys. Furthermore, the risk of overdose becomes insidious as meth might mask the early warning signs.

The Risks of Mixing Meth and Tapentadol

Tapentadol’s unique dual mechanism, acting both as an opioid and affecting norepinephrine levels, makes its combination with meth especially precarious. The co-usage can amplify central nervous system depression, rendering users prone to severe confusion, poor decision-making, and a heightened risk of accidents or self-harm.

The Risks of Mixing Meth and Methadone

Used both as a painkiller and a cornerstone in opioid replacement therapy, methadone has prolonged effects. Meth’s stimulating properties might push users to take more methadone to combat its depressive effects. This behavior can lead to a dangerous accumulation of methadone in the body, significantly heightening the overdose risk.

The Risks of Mixing Meth and Heroin

Heroin, an illicit opioid with a rapid onset of euphoric effects, is especially hazardous when used with meth. The body struggles to process the barrage of conflicting signals, with meth’s stimulatory effects clashing against heroin’s potent depressive properties. This can lead to unpredictable behavior, severe respiratory depression, and acute cardiac complications.

Understanding the intricacies of methamphetamine’s interactions with these opioids is paramount for both medical professionals and users. With this knowledge, preventive measures can be more effectively implemented, and potential hazards can be promptly identified and addressed.

Treatment Options for Polysubstance Addiction: Meth & Opioids

Engaging with substances such as methamphetamine and opioids is fraught with challenges. When these two potent substances are combined, the risks amplify, and the consequences can be dire. Recognizing the significance of timely and appropriate intervention becomes crucial for individuals and their surrounding communities.

Early Intervention

Early signs of drug usage can often be subtle. These might manifest as irregular sleeping patterns, erratic behaviors, changes in physical appearance, and dramatic mood swings. Recognizing these signs is instrumental in preempting more severe health repercussions and behavioral issues. Moreover, even before a full-blown addiction manifests, engaging with health professionals or counseling services can offer invaluable guidance on cessation methods and coping strategies.

Professional Rehabilitation

Professional rehabilitation centers provide a structured environment tailored to an individual’s needs. Within these facilities, programs are developed to address the multifaceted challenges of addiction. Typically, they incorporate medical detoxification, therapy sessions (both individual and group), and aftercare planning to ensure sustained recovery. Addressing the complexity of a dual addiction, such as that of meth and opioids, necessitates a holistic approach. It involves the combined expertise of medical professionals, therapists, and counselors to tackle both the physiological and psychological aspects of addiction.

Support Groups and Peer Counseling

Engaging with those who have endured similar trials and tribulations can be a source of immense comfort and guidance. Support groups facilitate an environment where experiences, coping strategies, and recovery stories are shared, creating a sense of mutual understanding and camaraderie. These regular interactions also instill a sense of accountability and responsibility, acting as a deterrent against potential relapses and promoting continual recovery.

Family and Community Involvement

The role of family and community in an individual’s recovery journey cannot be overstated. A supportive home environment, understanding peers, and informed communities can significantly influence the rehabilitation process. By equipping themselves with knowledge about addiction, families can provide the emotional and logistical support necessary for recovery. On a broader scale, community awareness programs can shine a light on the risks of co-usage and the available avenues for help, fostering a proactive and understanding societal approach.

Continuous Counseling and Therapy

The journey to recovery doesn’t end once initial rehabilitation is complete. Continuous counseling and therapy sessions play a pivotal role in ensuring that individuals remain on the path to recovery. They provide tools to handle triggers and stressors without resorting back to substance use. Beyond just maintaining sobriety, these sessions can be platforms for personal growth, helping individuals develop coping mechanisms, enhance self-awareness, and build a vision for their future.

Understanding the various avenues available for assistance and the critical importance of seeking help can be life-changing. It provides hope and a roadmap for those ensnared in the clutches of dual addiction, illuminating the path to a brighter, substance-free future.

Gallus Can Help

The dangers of combining methamphetamine and opioids are far-reaching, with profound implications for individual and public health. Overcoming such a formidable challenge necessitates specialized intervention and expertise. Gallus Medical Detox Centers stands at the forefront of this battle, dedicated to helping individuals regain control of their lives. With state-of-the-art facilities, compassionate professionals, and a proven approach, they offer a sanctuary for those seeking refuge from the storm of addiction.

If you or a loved one are grappling with the debilitating effects of opioids, meth, or their lethal combination, there’s no better time to act than now. Remember, the journey to recovery begins with a single step, and Gallus Medical Detox Centers is here to guide you every step of the way. Reach out today and embrace the chance to build a brighter, healthier future.

FAQs

What are the initial signs of someone using both meth and opioids?

Recognizing early signs is crucial for timely intervention. Combined usage of these drugs can manifest as extreme mood swings, erratic behavior, both increased energy and sudden lethargy, pronounced weight loss, dilated pupils, and visible skin sores. Furthermore, users may exhibit alternating periods of hyperactivity (due to meth) and pronounced drowsiness or nodding off (due to opioids).

Is there a safe amount to mix meth and opioids?

No combination of meth and opioids is deemed safe. Each drug on its own carries significant risks, and when combined, the potential hazards multiply. The body’s reaction to such a combination is unpredictable and can vary based on an individual’s health, metabolism, and tolerance.

How can someone seek help if they’re struggling with this combination?

Early intervention is vital. Those struggling or their loved ones should consider reaching out to local rehabilitation centers, addiction helplines, or medical professionals. Many communities also offer support groups where affected individuals can share experiences and resources.

Are there any medications to help someone detox from both substances?

While there are medications that aid in detoxification from each drug individually, it’s imperative to consult a medical professional for co-usage. Medications such as buprenorphine and methadone can be used for opioid dependence, while certain medications might help alleviate the symptoms of meth withdrawal.

How can the community support those struggling with this addiction?

Education, understanding, and compassion are fundamental. Communities can hold awareness campaigns, support local rehabilitation initiatives, and offer platforms for affected individuals and their families to share experiences. Creating a stigma-free environment encourages affected individuals to seek help.

Why is the combination of meth and opioids particularly dangerous?

Meth is a stimulant, and opioids are depressants. Their simultaneous consumption sends conflicting signals to the body, leading to immense strain on various systems, notably the cardiovascular and respiratory systems. Additionally, the combination increases the risk of overdose as the effects of one drug can mask the symptoms of too much of the other.

What are the long-term effects of co-using meth and opioids?

Prolonged co-usage can lead to severe cardiovascular issues, respiratory problems, cognitive impairments, kidney and liver damage, and increased susceptibility to infections due to a compromised immune system. Psychologically, users may face heightened anxiety, depression, paranoia, and other mental health challenges.

Can one become addicted after just one-time use of both substances?

While addiction typically develops over time, both meth and opioids are highly potent and can cause a strong physiological and psychological response. This might lead individuals to seek the combined effects repeatedly, rapidly setting the stage for potential addiction.

References

  1. Know the Risks of Meth. (n.d.). SAMHSA. https://www.samhsa.gov/meth
  2. What are the long-term effects of methamphetamine misuse? | National Institute on Drug Abuse. (2022, January 12). National Institute on Drug Abuse. https://nida.nih.gov/publications/research-reports/methamphetamine/what-are-long-term-effects-methamphetamine-misuse
  3. Division, D. C. (2023). What are opioids? HHS.gov. https://www.hhs.gov/opioids/prevention/index.html
  4. Prescription Opioids DrugFacts | National Institute on Drug Abuse. (2023b, May 25). National Institute on Drug Abuse. https://nida.nih.gov/publications/drugfacts/prescription-opioids
  5. Opioid complications and side effects. (2008, March 1). PubMed. https://pubmed.ncbi.nlm.nih.gov/18443635/
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  8. Meth and heart disease: A deadly crisis we don’t fully fathom, report says. (2021, August 16). www.heart.org. https://www.heart.org/en/news/2019/08/21/meth-and-heart-disease-a-deadly-crisis-we-dont-fully-fathom-report-says
  9. Glasner-Edwards, S., & Mooney, L. (2014b). Methamphetamine Psychosis: Epidemiology and management. CNS Drugs, 28(12), 1115–1126. https://doi.org/10.1007/s40263-014-0209-8
  10. Hydrocodone: MedlinePlus drug information. (n.d.-b). https://medlineplus.gov/druginfo/meds/a614045.html
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  12. Oxycodone: MedlinePlus drug information. (n.d.-b). https://medlineplus.gov/druginfo/meds/a682132.html
  13. Morphine: MedlinePlus drug information. (n.d.-c). https://medlineplus.gov/druginfo/meds/a682133.html
  14. Codeine: MedlinePlus Drug Information. (n.d.). https://medlineplus.gov/druginfo/meds/a682065.html
  15. Fentanyl Facts. (n.d.-b). https://www.cdc.gov/stopoverdose/fentanyl/index.html
  16. Hydromorphone: MedlinePlus Drug Information. (n.d.). https://medlineplus.gov/druginfo/meds/a682013.html
  17. Tapentadol: MedlinePlus drug information. (n.d.-b). https://medlineplus.gov/druginfo/meds/a610006.html
  18. Methadone: MedlinePlus drug information. (n.d.-b). https://medlineplus.gov/druginfo/meds/a682134.html
  19. National Library of Medicine. (n.d.-a). Heroin. https://medlineplus.gov/heroin.html

 

Shannon Weir, RN

Shannon Weir, RN is the Chief Nursing Officer at Gallus Medical Detox Centers. She has been a Registered Nurse for 30 years, Shannon’s experience ranges from critical care to flight nursing, medical detox, sexual assault exams, and SWAT nursing. Shannon has been with Gallus Medical Detox Centers since 2010 and is a vital part of our organization.

Last medically reviewed on September 11, 2023

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shannon weir Shannon Weir, RN
Nov 18, 2023

If you or a loved one is struggling with substance use, call Gallus at
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