The Dangers of Combining Percocet and Xanax

In the realm of medications, understanding drug interactions is paramount to ensure one’s safety and well-being. Two such drugs that raise significant concerns when combined are Percocet and Xanax. Individually, these medications serve crucial roles for those they’re prescribed to; however, the risk factors dramatically increase when they’re taken together. Let’s delve into the dangers of mixing these two potent substances.

Understanding Percocet

Percocet stands as a powerful medication in pain management. Formulated by combining acetaminophen and oxycodone, it’s especially effective for moderate to severe pain.

At its core, Percocet blends the pain-relieving properties of acetaminophen with the narcotic effects of oxycodone. Acetaminophen, commonly known for its presence in over-the-counter pain relievers, is combined with oxycodone to enhance its efficacy and provide sustained relief.  As the primary narcotic element in Percocet, oxycodone operates by affecting the brain’s pain receptors. This interference helps in reducing the sensation of pain, providing much-needed relief to the user.

Common Side Effects of Percocet

• Drowsiness
• Mild itching or skin rash
• Dizziness
• Constipation
• Nausea
• Vomiting
• Blurred vision
• Dry mouth

Severe Side Effects of Percocet

• Shallow or weak breathing
• Slow heart rate or weak pulse
• Confusion or unusual thoughts
• Seizures (convulsions)
• Adrenal gland disorders, manifesting as nausea, vomiting, loss of appetite, dizziness, etc.
• Liver problems, which might present with symptoms like nausea, upper stomach pain, tiredness, loss of appetite, dark urine, and jaundice (yellowing of the skin or eyes)
• Low cortisol levels leading to vomiting, dizziness, worsening tiredness, or weakness
• High levels of serotonin in the body leading to agitation, hallucinations, fever, muscle stiffness, etc.

Like all opioid medications, Percocet comes with a risk of addiction. Regular monitoring and adherence to prescribed doses are essential to prevent dependency and other potential side effects.

Understanding Xanax

Xanax, or alprazolam, falls under the benzodiazepine class of medications. Its primary role is to provide relief from anxiety and panic disorders.

Anxiety and panic disorders can be debilitating for many. Xanax acts as a reprieve, helping to calm the overactivity in the brain that these conditions often trigger.  The effectiveness of Xanax stems from its ability to slow down the central nervous system. By doing this, it induces a state of relaxation and reduces symptoms of anxiety and panic.

Common Side Effects of Xanax

• Drowsiness
• Dizziness
• Sleepiness
• Slurred speech
• Memory problems
• Poor balance or coordination
• Feeling anxious early in the morning

Severe Side Effects of Xanax

• Depressed mood or thoughts of suicide
• Racing thoughts, increased energy, risk-taking behavior
• Confusion, agitation, hostility
• Hallucinations
• Uncontrolled muscle movements, tremor
• Seizures
• Chest pain, pounding heartbeats, or fluttering in the chest
• Jaundice (yellowing of the skin or eyes)

The calming nature of Xanax makes it a drug with the potential for dependency. Prolonged usage or misuse can lead to addiction. As such, it’s crucial that patients adhere strictly to their prescribed dose and duration, and always consult their healthcare provider regarding any concerns.

Consequences of Combining Percocet and Xanax

When Percocet and Xanax are taken together, the interaction between these two medications can result in a range of amplified and often dangerous effects. Both drugs are central nervous system (CNS) depressants, meaning they can slow down brain activity. This combined effect has several implications:

Amplified CNS Depression

When combined, the CNS depressant effects of Percocet and Xanax can be magnified. This can lead to profound drowsiness, mental confusion, and decreased alertness. Over time, this pronounced sedation can interfere with daily activities, rendering tasks like driving, operating machinery, or even making clear decisions hazardous.

Respiratory Depression

Both drugs, especially when taken together, can depress respiratory functions. This means they can slow or weaken the respiratory system, reducing the oxygen that reaches the brain and other vital organs. In extreme cases, this can lead to respiratory arrest, where breathing stops altogether. Such scenarios are life-threatening and demand immediate medical intervention.

Heightened Risk of Overdose

Taking multiple CNS depressants increases the risk of an accidental overdose. Signs of overdose might include extreme drowsiness, difficulty waking up, slow or shallow breathing, bluish-colored or cold skin, and loss of consciousness. The presence of these symptoms should trigger an immediate call for emergency services.

Impaired Cognitive and Motor Functions

The combined effect of Percocet and Xanax can severely impair both cognitive and motor functions. This results in slowed thinking, memory issues, impaired judgment, and reduced motor coordination. Such effects can render seemingly simple tasks dangerous and increase the risk of accidents.

Dependency and Withdrawal

Both drugs have the potential for dependency. When used together, there’s an increased risk of becoming dependent on both substances. Discontinuing or reducing the dose without proper medical guidance can lead to withdrawal symptoms, which can be both intense and harmful.

Increased Risk with Alcohol

Adding alcohol to the mix further increases the risks. Alcohol, being another CNS depressant, can multiply the sedative effects, making it an even more dangerous combination. This can result in a deeper state of sedation, reduced respiratory function, and a heightened risk of a fatal overdose.

Safe Usage and Monitoring

Medications like Percocet and Xanax have therapeutic purposes but also come with their share of risks. To ensure the benefits outweigh the potential harms, one must adhere to strict guidelines and safety measures.

Open Communication with Healthcare Providers

Regular check-ins with your doctor are vital. These appointments are opportunities to discuss any changes in symptoms, potential side effects, or concerns about dependency. Always inform your doctor about any new medications, supplements, or herbal remedies you’re taking. Some substances can interact with your prescribed medications in unforeseen ways.

Dosage Discipline

Stick to the prescribed dosage. Taking more than advised can lead to increased risks, including dependency or overdose. Avoid the temptation to self-adjust your dosage based on how you feel. Any changes should be discussed with a healthcare professional.

Education and Awareness

Understand your medication. Familiarize yourself with its purpose, potential side effects, and interactions. Be proactive in recognizing early signs of side effects or complications. This timely awareness can be the difference between a manageable symptom and a medical emergency.

Avoid Alcohol and Other Depressants:

When on CNS depressant medications, refrain from consuming alcohol or other depressant substances unless expressly approved by a doctor.  Combining depressants amplifies their effects, elevating the risk of accidents, respiratory depression, and fatal overdose.

Routine Monitoring

Regularly monitor your body’s response. This includes checking for any signs of increased tolerance, where larger doses are needed for the same effect, or signs of withdrawal when not on the medication.

For those on long-term prescriptions, routine liver and kidney function tests can be beneficial as these organs process medications and can be affected over time.

Planning for Discontinuation

If there’s a need to discontinue the medication, do it under the guidance of a healthcare professional. Abruptly stopping can lead to severe withdrawal symptoms.

Your doctor can devise a tapering plan to gradually reduce the dosage, minimizing any adverse effects.

Medications like Percocet and Xanax can offer relief and treatment for specific conditions, their potent nature necessitates careful usage and monitoring. Being proactive, educated, and maintaining open communication lines with healthcare providers are fundamental for the safe and effective use of these drugs.

Gallus Can Help

While medications like Percocet and Xanax offer relief and treatment for specific conditions, their potent nature necessitates careful usage and monitoring. Being proactive, educated, and maintaining open communication lines with healthcare providers is fundamental for the safe and effective use of these drugs.

If you or a loved one are struggling with opioid addiction or dependencies on other substances, remember that help is available. Gallus Medical Detox is an addiction treatment center equipped with experienced professionals dedicated to guiding individuals through their recovery journey. Understanding that each person’s path to recovery is unique, Gallus ensures personalized, evidence-based treatment approaches.

Don’t let addiction hold you or your loved ones back from living a full and meaningful life. Reach out to Gallus Medical Detox, either by giving them a call or taking their online self-assessment. Recognizing the problem is the first step, and seeking professional help is the bridge to a brighter, addiction-free future. Call 866-272-5978 today.

FAQs

What is Percocet used for?

Percocet is primarily prescribed to manage moderate to severe pain. It contains a combination of acetaminophen and oxycodone.

Why is Xanax prescribed?

Xanax, or alprazolam, belongs to the benzodiazepine class and is often prescribed to treat anxiety and panic disorders.

Can I take Percocet and Xanax together?

Combining Percocet and Xanax can lead to severe side effects due to their mutual CNS depressant properties. It’s crucial to consult with a healthcare provider before taking both medications together.

What are the dangers of mixing Percocet, Xanax, and alcohol?

All three substances are CNS depressants. When combined, they can amplify each other’s effects, leading to profound sedation, respiratory distress, and even fatal overdose.

What should I do if I experience severe side effects?

If you experience severe side effects or suspect an overdose, seek emergency medical attention immediately. Side effects like shallow breathing, confusion, and loss of consciousness are particularly concerning.

I’ve been taking Percocet and Xanax for a while; can I stop abruptly?

Stopping either medication suddenly, especially after prolonged use, can lead to withdrawal symptoms. It’s essential to consult a healthcare provider about safely discontinuing use.

References

1. Percocet: Uses, Dosage, Side Effects & Warnings. (n.d.-b). Drugs.com. https://www.drugs.com/percocet.html
2. Acetaminophen: MedlinePlus drug information. (n.d.-b). https://medlineplus.gov/druginfo/meds/a681004.html
3. Oxycodone: MedlinePlus drug information. (n.d.-b). https://medlineplus.gov/druginfo/meds/a682132.html
4. Alprazolam: MedlinePlus drug information. (n.d.-c). https://medlineplus.gov/druginfo/meds/a684001.html
5. Drug interaction report: Percocet, Xanax. (n.d.). Drugs.com. https://www.drugs.com/interactions-check.php?drug_list=72-1135,133-54
6. Pietrangelo, A. (2018b, August 15). Understanding Central nervous system (CNS) depression: symptoms, treatment, and more. Healthline. https://www.healthline.com/health/depression/cns-depression
7. Benzodiazepines and opioids | National Institute on Drug Abuse. (2023, March 6). National Institute on Drug Abuse. https://nida.nih.gov/research-topics/opioids/benzodiazepines-opioids

Shannon Weir, RN

Shannon Weir, RN is the Chief Nursing Officer at Gallus Medical Detox Centers. She has been a Registered Nurse for 30 years, Shannon’s experience ranges from critical care to flight nursing, medical detox, sexual assault exams, and SWAT nursing. Shannon has been with Gallus Medical Detox Centers since 2010 and is a vital part of our organization.