The Pulse



mortality risk
Highly likely
mortality risk


An atypical antidepressant and neurorestorative agent. It is also a mu-opioid receptor agonist, which at high doses works just like any other opioid. It has a long half life and is very addictive.

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What is it?

It is not FDA approved in the US. It was scheduled in Michigan as a schedule 2 narcotic, and Alabama is currently working through doing the same thing. The CDC has identified it as an emerging public health risk, as its use is becoming popular, and there are being more and more deaths reported as being directly related to Tianeptine. Particularly when also being taken with Phenibut. Appears to be very hepatotoxic (liver toxic) at higher doses, but not well studied. It can be reversed by Naloxone, but is not always recognized as an opioid overdose. Interestingly enough, it wasn’t until recently it has been seen as an addictive substance, in fact there are many research articles from 2017 and prior that state it is not addictive and works well as an antidepressant.

Other names

Tia, ZaZa Reds, ZaZa Whites


Where do people get it?

Gas stations, online.

How is it dangerous?

It has a long half-life, not detectable in normal urine drug screens, and from anecdotal reports does not always respond well to Sub.

If you or a loved one is struggling with substance use, call Gallus at
(888) 306-3122.